Hospital Work Package (WP1)

Hospital work package (WP1)

Leader: Dr. Patrice Piola, IPC, Phnom Penh, Cambodia

This “Hospital work package” will describe the landscape of antibioresistance in patients from two hospitals in Cambodia, one in the capital (urban, Phnom Penh) and the other in a remote province (rural, Battambang).

In this work package, the following resistant bacteria are expected to be detected in the clinical bacteriology laboratories of the two collaborating hospitals:

Extended spectrum beta-lactamase Enterobacteriaceae (ESBLE)

Carbapenemase-producing Enterobacteriaceae (CPE)

Methicillin-Resistant Staphylococcus aureus (MRSA)

Salmonella spp. resistant to Fluoroquinolone (FQ-resistant Salmonella)


Hospitalized patients presenting ABR could be the starting point of studies exploring the circulation of ABR between humans, animals, and the environment in a “One Health” approach. Animal and environmental factors in the households of rural patients infected with ABR bacteria may contribute to the ABR emergence and transmission. This knowledge could guide targeted ABR control strategies.

WP1 objectives

Overarching objective:  Carry out bacterial cultures on patients who have been hospitalized for less than 2 days in two Cambodian public hospitals: Battambang Provincial Hospital (North-West Province) and Calmette Hospital (Phnom Penh).

Specific objective: Compare bacteria isolated from patients living with ABR between a capital city hospital (Calmette Hospital Phnom Penh) and a provincial hospital (Battambang Provincial Referral, Battambang).